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Xerosis – Symptoms, causes and solutions


Xerosis – Symptoms, causes and solutions

  • What is Xerosis?
  • Xerosis-Signs and Symptoms 
  • Xerosis --What causes it?
  • Xerosis --What can be done?

Most people have experienced Xerosis, or dry skin, at some stage of their life. When it becomes severe it can affect people both physically and emotionally.   Understanding the various causes and the relevant solutions helps you to tailor your routine to your skin’s needs, enhance its efficacy and control the symptoms of Xerosis.



What is Xerosis?




Xerosis is the medical name for dry skin. It comes from Greek: ‘xero’ means ‘dry’ and ‘osis’ means ‘disease’ or ‘medical disorder’. Xerosis is caused by a lack of moisture in the skin, which may be the result of ageing (senile Xerosis) or due to underlying diseases such as Diabetes. The result is dry, or very dry, rough and tight skin,  which can progress to become extremely rough and scaly, flaky and itchy.


Attention Box

If you are unsure about your skin condition consult a dermatologist for a face-to-face diagnosis. 

Dry skin is unable to regulate its moisture content as effectively as normal skin.Internal and external factors can disrupt skin hydration.

 Skin’s ability to regulate the amount of water in its upper layers depends on three different factors:

  • The efficiency of the hygroscopic molecules in the epidermal layers of skin. In normal skin, molecules such as Urea, Lactate, PCA (Pyrrolidone Carboxylic Acid), salts and amino acids attract and bind in water.
  • The effectiveness of skin´s own barrier lipids (e.g. Cemamide) which perform the vital function of reducing water loss due to evaporation.

In normal skin, this delicate system works well and adapts to the skin’s hydration requirements, maintaining an adequate concentration of water in a changing environment. However, several internal (endogenous) and external (exogenous) factors can disrupt this system and cause skin to dry out. 

Xerosis – signs and symptoms

Xerosis is a common condition experienced by millions of people, either chronically (repeatedly) or acutely (a one-off occurrence). Just as multiple factors support skin hydration, a lack of water within the skin can present in a variety of ways. Dry Skin will normally display a couple of these symptoms, while very dry skin commonly has all of these symptoms to some degree:

Itching can be one of the symptoms of dry, tight skin.Dry, rough and tight skin can also occur on the face.

  • Tightness is caused when the number of dead skin cells increases, leaving a layer on skin’s surface that causes it to dry out and feel tight.
  • Roughness is also caused by dryness. This dryness increases the rate at which skin cells die off, leaving a thicker layer of dead cells at the skin’s surface which makes it feel rough.
  • Flaky skin occurs when the large scales of the epidermis peel off and sometimes may be seen as a fine dust.
  • Itching is another result of dryness and is an impulsive reaction to the discomfort caused by tight, poorly functioning skin. The urge to scratch increases according to the severity of the dryness.

Dry skin can occur on any area of the body, although some areas are more affected than others.

Skin conditions such as Atopic Dermatitis, Keratosis Pilaris, Ichthyosis and Psoriasis predominantly cause localised areas of xerotic skin. Read more about Psoriasis, Atopic Dermatitis on face or body or about atopic children´s skin on face or body.

Attention Box

Always seek professional advice for a face-to-face diagnosis if you develop any of these symptoms.

Xerosis – what causes it?

Two key deficiencies in the skin have been shown to contribute to Xerosis:

When skin lacks lipids or Natural Moisturising Factors it can become dry and damaged.

A deficiency in skin barrier lipids
The cells in the horny layer are bound together by epidermal lipids. These lipids are essential for healthy skin: they create its protective barrier and bind in moisture. When lipids are missing, skin can become dry and may feel tight and rough.

A deficiency of Natural Moisturising Factors (NMF)

Skin contains several other natural moisturising factors (NMF) 
 in addition to Urea.  These are Lactate, PCA, salts and sugars. Like Urea, these NMF attract moisture and bind it into the Stratum corneum, or upper layer of the skin, preventing it from becoming dry, scaly and damaged.

Factors that contribute to dry skin

Several external factors initiate the physiological changes (mentioned above) that may lead to Xerosis:

Environmental factors, such as cold, can influence physiological changes.  Washing too frequently can damage skin´s natural barrier.  Some medications can dehydrate the body.

The skin’s external environment – humidity, inappropriate cleansing and sunlight
- Dry skin is more common when environmental humidity is low, which occurs in the winter and sometimes during a hot summer.
- Inappropriate cleansing (washing skin too frequently with products that strip it of its natural lipids) can damage the skin’s natural barrier. 
- Sunlight can cause skin dryness as the UV light increases the rate of water evaporation from the skin. In the longer term, this can cause skin to age prematurely which affects its ability to maintain adequate hydration.

The skin’s internal environment – age, dehydration, diet, medication and disease

- Studies have reported that lipid levels in the stratum corneum
 reduce with ageing. This can lead to age-induced dryness.
- When the body is dehydrated skin is at greater risk of becoming dry.
- Diet is important as vital nutrients are necessary for healthy skin.
- Certain medications, particularly diuretics, cause the body to become dehydrated, which in turn can lead to Xerosis.
- Skin conditions such as Atopic Dermatitis,  Keratosis Pilaris, Ichthyosis and Psoriasis include dry skin as a common symptom.
- Diabetes can also cause dry skin.

Xerosis – what can be done?

 Historically, the treatment of Xerosis has been primarily symptomatic. The aim being the short-term relief of symptoms through the topical application of lipids, mainly vegetable oils, humectants and NMF such as Urea. As more is understood about the causes and triggers of Xerosis, clinicians have discovered that a more holistic, enduring approach to treating Xerosis yields superior results. This strategy begins with avoiding, or minimising, the causes and contributing factors of Xerosis and centres on maintaining an adequate Skincare routine for face and body, featuring both cleansing and moisturising. 

Cleansing dry skin

Use mild cleansers to protect dry skin, such as our collagen facial cleanser

Mild but effective skin cleansing is an essential first step before applying any emollients and moisturisers specially formulated to care for dry skin. Choose a mild cleansing product which has been proven not to compromise skin’s barrier function. This will prevent the skin from drying out and support the efficacy of subsequent skin moisturising treatments.Mild but effective skin cleansing is an essential first step before applying any emollients and moisturisers specially formulated to care for dry skin. Choose a mild cleansing product which has been proven not to compromise skin’s barrier function. This will prevent the skin from drying out and support the efficacy of subsequent skin moisturising treatments.

Improving skin hydration

There are many different factors that cause and influence skin hydration. Each of these factors should be addressed in order to effectively treat Xerosis.

Urea is often deficient in dry skin and therefore a common ingredient in moisturisers. Additional causes of Xerosis are a lack of other NMF and skin barrier lipids. Supplying these vital molecules topically can restore the skin’s ability to regulate hydration.

Moisturisers containing a range of NMF (including Urea) and  Ceramide have been clinically proven to provide superior skin hydration and longer-lasting moisturisation to formulas containing just Urea. This discovery represents an advancement in the treatment of Xerosis. 

Collagen contains hydrophilic natural moisturizing factors and has strong permeability to the skin. It can combine with cells on the skin through the stratum corneum, participate in and improve the metabolism of skin cells, and enhance the activity of collagen in the skin.


The existence of collagen makes the reticular fibers of the dermis more elastic and tenacious. At the same time, it also plays a key role - storing water, sufficient collagen, and the skin is not easy to lose water, including the repair of skin damage, which is inseparable from the contribution of collagen!

Avoiding contributing factors


In addition to a good cleansing and moisturising routine, it’s important to avoid factors that contribute to dry skin. The following precautions will help reduce the impact of dry skin and the need for treatment:

  • Avoid dry air by spending less time outdoors in hot, arid or cold weather and by using a humidifier indoors when the heating is on.
  • Reduce the time spent in hot water by having quick, lukewarm showers instead of long, hot showers or baths. 
  • Using gloves when washing dishes will help to avoid direct contact with hot water and strong detergents. 
  • Wear clothes made of natural materials such as cotton and silk that do not irritate the skin. Wool is natural but may cause irritation to extremely dry or atopic skin and should be avoided by people with these conditions. 
  • Use a laundry detergent that is free from dyes or perfumes. These can remain on clothes after washing and might irritate dry skin.
  • This article source from https://int.eucerin.com/about-skin/indications/xerosis  


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